Nginx
47 splinters use it.
nginx [engine x] is an HTTP and reverse proxy server, as well as a mail proxy server, written by Igor Sysoev. For a long time, it has been running on many heavily loaded Russian sites including Yandex, Mail.Ru, VKontakte, and Rambler. According to Netcraft nginx served or proxied 7.84% busiest sites in October 2011. Here are some of the success stories: FastMail.FM, Wordpress.com.